刘红林教授
姓名：刘红林
性别：男
职称：教授
最高学历：博士
毕业院校：南京师范大学
专业领域：动物遗传育种与繁殖
研究方向：动物分子育种；动物繁殖性状的调控
参加学术团体及任职情况
中国畜牧兽医学会理事；中国畜牧兽医学会畜禽遗传标记学会副理事长；中国畜牧兽医学会动物遗传育种学会常务理事；江苏省畜牧兽医学会副理事长；江苏省动物学会副理事长
承担项目
1、“卵泡闭锁的分子机制”（2007CB947403），2007-2010，“973”子课题，主持。经费550万元 2、“节粮型高瘦肉率转基因猪新品种培育”（2008ZX08006-003），2008-2015，转基因生物新品种培育重大专项子任务，主持。经费700万元 3、“猪肉质性状的表观遗传学调控”（2007AA10Z100），2007-2010，“863”课题，主持。经费70万元 4、“小鼠卵细胞质对供体核DNA甲基化和印记基因表达的调控”（304771244），2005-2007，国家自然科学基金，主持。经费19万元 5、“组蛋白去乙酰化对小鼠核移植胚基因组重序的调控”（30371034），2006-2008，国家自然科学基金，主持。经费19万元 6、“DOT1调节卵母细胞减数分裂的机制及其对胚胎早期发育的影响”（30771552），2008-2010，国家自然科学基金，主持。经费30万元 7、“JMJD2 蛋白家族对小鼠早期胚胎H3K9 甲基化修饰及发育能力的影响”（31072028），2011-2013，国家自然科学基金，主持。经费38万元 8、let-7家族miRNA调控猪卵泡闭锁的分子机制(31172187)，2012-2015，国家自然科学基金，主持。经费58万元 9、杂交细胞中小鼠ES细胞诱导体细胞核基因组重序的分子机制（NCET-05-0493），2006-2009，教育部新世纪优秀人才支持计划，主持，经费35万元 10、结合分子标记辅助选择加速育成新淮猪瘦肉型新品系（BG2004317），2004-2007，江苏省高技术研究，主持，20万元 11、家禽生物反应器研究（2007AA100504），2007-2010，863重点项目，子课题主持，经费40万元 12、猪发情障碍的内分泌与表观遗传机理（2014CB138502），2014-2018，“973”子课题，主持，480万元 13、猪肝脏IGF1基因表达调控机制研究（31472073），2015-2019，国家自然科学基金，主持，88万元
奖励及荣誉
教育部“新世纪优秀人才支持计划”；江苏省“六大高峰人才”高层次人才；近年来获上海市科技进步二等奖、中华农业科技奖二等奖各一次；获国家优秀教学成果二等奖、江苏省优秀教学成果奖一、二等奖各一次。
论文论著
近三年发表部分论文（*: 通信作者）
1.Wangjun Wu, Zhuqing Ren, Pinghua Li, Debing Yu, Jie Chen, Ruihua Huang, Honglin Liu*. Six1: A critical transcription factor in tumorigenesis. International Journal of Cancer, 2014 (Online, IF: 6.198)
2.Jia-Qing Zhang, Ming Shen, Cheng-Cheng Zhu, Feng-Xiang Yu, Ze-Qun Liu, Nazim Ally, Shao-Chen Sun, Kui Li, Hong-Lin Liu*. 3-Nitropropionic Acid Induces Ovarian Oxidative Stress and Impairs Follicle in Mouse. PLoS ONE, 2014, 9(2): e86589
3.Shaochen Sun, Xuguang Wang, Xueshan Ma, Xianju Huang, Juan Li, Honglin Liu*. TBP Dynamics during Mouse Oocyte Meiotic Maturation and Early Embryo Development. PLoS ONE, 2013, 8(1): e55425
4.Peng Xiao, Xiao-long Zhou, Hong-xiao Zhang, Kai Xiong, Yun Teng, Xian-ju Huang, Rui Cao, Yi Wang, Hong-lin Liu*. Characterization of the nuclear localization signal of the mouse TET3 protein. Biochemical and Biophysical Research Communications, 2013, 439: 373-377
5.Xian-ju Huang, Xuguang Wang, Xueshan Ma, Shao-Chen Sun, Xiaolong Zhou, Chengcheng Zhu, and Honglin Liu*. EZH2 is essential for development of mouse preimplantation embryos. Reprodution, Fertility and Development, 2013, on line.
6.Kai Xiong, Shanshan Li, Hongxiao Zhang, Ye Cui, Debing Yu, Yan Li, Wenxing Sun, Yingying Fu, Yun Teng, Zhi Liu, Xiaolong Zhou, Peng Xiao, Juan Li, Honglin Liu, Jie Chen. Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling. Mol Biol Rep (2013) 40:4251–4256
7.Fulu Dong, Zhenwei Song, Jinping Zhang, Youde Lu, Chunlei Song, BaoChun Jiang, Baole Zhang, Peiqing Cong, Hongyan Sun, Fangxiong Shi and Honglin Liu*. Global transcriptional analysis of nuclear reprogramming in the transition from MEFs to iPSCs. Genes to Cells (2013) 18, 42–55 (Correponding author)
8.Xiong K, Wu W, Wang X, Ma X, Chen J, Liu H*. Mouse oocyte meiosis is disturbed by knockdown of Suv4-20h. Reprod Fertil Dev.2013，25，503-510
9.Yanhui FU, Fei LIN and Honglin LIU*. Changes in the messenger RNA expression levels of Bcl-2 family members and caspase-8 and-3 inporcine ovarian follicles during follicular atresia. Animal Science Journal 2013，84：222-230
10.Ming Shen, Fei Lin, Jiaqing Zhang, Yiting Tang,Wei-Kang Chen and Honglin Liu*. Involvement of the Up-regulated FoxO1 Expression in Follicular Granulosa Cell Apoptosis Induced by Oxidative Stress. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 2012, Vol 287（31）：25727-25740
11.Xinhua Hou, Zhonglin Tang, Honglin Liu*, Ning Wang, Huiming Ju, Kui Li. Discovery of MicroRNAs Associated with Myogenesis by Deep Sequencing of Serial Developmental Skeletal Muscles in Pigs. PLoS ONE, 2012, 7(12): 52123
12.F.L. Dong, H.A. Kaleri, Y.D. Lu, C.L. Song, B.C. Jiang, B.L. Zhang, L.J. Wang, X.G. Wang, X.S. Ma, B.J. Wu, H. Song, J. Li and H.L. Liu*. Generation of induced pluripotent mouse stem cells in an indirect co-culture system. Genetics and Molecular Research, 2012, 11 (4): 4179-4186
13.Sun, Shao-Chen, Liu Hong-Lin, Sun, Qing-Yuan. Survivin regulates PIK1 localization to kinetochore in mouse oocyte meiosis. Biochemical and Biophysical Research Communications, 2012, 421(4): 797-800
14.Zhang, Shumin, Xiong, Kai, Xie, Zhourui, Nan, Wenting, Liu, Honglin, Chen, jie. Stable silencing of beta-lactoglobulin (BLG) gene by lentivirus-mediated RNAi in goat fetal fibroblasts. Genetics and Molecular Biology, 2012, 35(3): 680-685
15.Chen, Jie, Liu, Huiling, Cai, Yafei, Wang, Genlin, Liu, Honglin, Li, Jing. Mutations in the exon 10 of prolactin receptor gene change the egg production performance in Wanjiang white goose. Molecular Biology Reports, 2012, 39(1), pp 475-483
16.Liu Jun, Qiaochu Wang, Fei Wang, Xing Duan, Xiaoxin Dai, Teng Wang, Honglin Liu, Xiangshun Cui, Nam-Hyung Kim, Shaochen Sun. Nucleation promoting factors regulate the expression and localization of Arp2/3 complex during meiosis of mouse oocytes. PloS ONE, 2012, 7(12):52277
17.Youde Lu, Fulu Dong, Chunlei Song, Huanhuam Wang, Changwan Du, Jing Han, Ling Qin, Le Zhai, Fang Zhao, Zhourui Xie and Honglin Liu*. Generate Induced Pluripotent Stem Cells by Three Factors under Feeder-Free Condition with Hinger Efficiencies. Journal of Animal and Vererinary Advances, 2012, 11(12):2110-2115
18.N. Ally, X.L. Zou, B.C. Jiang, L. Qin, L. Zhai, P. Xiao and H.L. Liu*. Inhibition of vascular endothelial growth factor A expression in mouse granulosa cells by lentivector-mediated RNAi. Genetics and Molecular Research, 2012, 11(4):4019-4033
19.Zengxiang Pan, Junlei Zhang, Jinbi Zhang, Bo Zhou, Jie Chen, Zhihua Jiang and Honglin Liu*. Expression Profiles of the Insulin-like Growth Factor System Components in Liver Tissue during Embryonic and Postnatal Growth of Erhualian and Yorkshire Reciprocal Cross F1 Pigs. Asian-Aust. J. Anim. Sci., 2012, Vol. 25, No. 7 : 903 - 912
20.Zengxiang Pan, Jinbi Zhang, Fei Lin, Xueshan Ma, Xuguang Wang, Honglin Liu*. Expression profiles of key candidate genes involved in steroidogenesis during follicular atresia in the pig ovary. Mol Biol Rep, 2012 Dec;39(12):10823-32
21.B.C. Jiang, D.B. Yu, L.J. Wang, F.L. Dong, H.A. Kaleri X.-G. Wang, N. Ali, J. Li and H.L. Liu*. Doxycycline-regulated growth hormone gene expression system for swine. Genetics and Molecular Research, 2012, 11(3):2946-2957
22.Fei Lin, Ran Li, Zeng xiang Pan, Bo Zhou, De bing Yu, Xu guang Wang, Xue shan Ma, Jing Han, Ming Shen, Hong lin Liu*. miR-26b Promotes Granulosa Cell Apoptosis by Targeting ATM during Follicular Atresia in Porcine Ovary. PLoS ONE, 2012, 7(6):38640
23.Zengxiang Pan, Jinbi Zhang, Qifa Li, Yinxia Li, Fangxiong Shi, Zhuang Xie, Honglin Liu*. Current Advances in Epigenetic Modification and Alteration during Mammalian Ovarian Folliculogenesis. Journal of Genetics and Genomics, 2012, 39: 111-123 (Correponding author)
24.Yafei Cai, Jun Li, Shiyong Yang, Ping Li, Xuan Zhang, Honglin Liu*. CIBZ, a Novel BTB Domain-Containing Protein, Is Involved in Mouse Spinal Cord Injury via Mitochondrial Pathway Independent of p53 Gene. PLoS ONE, 2012, 7(3): 33156
25.B.C. Jiang, H.A. Kaleri, H.X. Zhang, J. Chen, and H.L. Liu*. Application of the Sleeping Beauty system in Saanen goat fibroblast cells for establishing persistent transgene expression. Genetics and Molecular Research, 2011, 10(4): 3347-3355
26.Wang, LJ; Zhang, GM; Lin, F; Jiang, BC; Dong, FL; Liu, HL*. Expression of the insulin-like growth factor system in skeletal muscle during embryonic and postnatal development in the first filial generation pigs from Erhualian and Yorkshire reciprocal crosses. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2011, 173: 56-62
27.H.A. Kaleri, S.Y. Xu, and H.L. Liu*. Generation of transgenic chicks using an oviduct-specific expression system. Genetics and Molecular Research, 2011, 10 (4): 3046-3055
28.Shiyong Xu, Hubdar Ali Kaleri and Honglin Liu*. Effect of First Intron on Ovalbumin Promoter Activity. Pakistan J. Zool., 2011, 43(6): 1183-1189
